Burst and tonic firing
From neurov.is/on
Thalamic relay neurons, such as that of the LGN have two distinct modes[1]:
- Burst firing - neuron alternates between bursts of very large firing rates and silent intervals.
- Tonic firing - neuron fires sporadically.
[edit] Burst firing
Burst firing is caused by a IT current (see [1] ), which depolarizes the membrane potential closer to the firing threshold, called the low threshold spike. Burst firing is more detectable to visual stimuli (??) [1]. Crick[2] suggested that burst firing plays an important role in attention.
[edit] Tonic firing
Tonic firing is better at encoding linear responses[1].
[edit] References
- ↑ 1.0 1.1 1.2 1.3 S.Murray Sherman (2001). "Tonic and burst firing: dual modes of thalamocortical relay". Trends in Neurosciences 24 (2): 122-126.
- ↑ F. Crick (1984). "Function of the thalamic reticular complex: the searchlight hypothesis". Proc. Natl Acad. Sci. USA 81: 4586-4590.
- Grubb, Matthew S.; Thompson, Ian D. (2005). "Visual Response Properties of Burst and Tonic Firing in the Mouse Dorsal Lateral Geniculate Nucleus". J Neurophysiol 93: 3224-3247.
- Burst Firing is a Neural Code in an Insect Auditory System Hugo G. Eyherabide, Ariel Rokem, Andreas V. M. Herz, and Inés Samengo Front Comput Neurosci. 2008; 2: 3.
